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Article

Distinct clinical outcomes for cytogenetic abnormalities evolving from aplastic anemia

1 May 2002

Abstract excerpt

A serious complication of aplastic anemia (AA) is its evolution to clonal hematologic diseases such as myelodysplasia (MDS) and leukemia, which is usually associated with the appearance of a cytogenetic abnormality in bone marrow cells. We present here an analysis of a cohort of 30 patients with otherwise typical AA in whom clonal karyotypic evolution was observed during frequent periodic marrow examinations. The...

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Identifiers

PMID: 11964274
DOI: 10.1182/blood.v99.9.3129

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