Article
The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct.
Acta crystallographica. Section D, Biological crystallography - 1 Jun 2004
Messens Joris, Van Molle Inge, Vanhaesebrouck Peter, Van Belle Karolien, Wahni Khadija, Martins José C, Wyns Lode, Loris Remy
Abstract excerpt
Structural insights into formation of the complex between the ubiquitous thiol-disulfide oxidoreductase thioredoxin and its oxidized substrate are under-documented owing to its entropical instability. In vitro, it is possible via a reaction with 5,5'-dithiobis-(2-nitrobenzoic acid) to make a stable mixed-disulfide complex between thioredoxin from Staphylococcus aureus and one of its substrates, oxidized pI258...
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