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Conformational analysis and chemical reactivity of the multidomain sulfurtransferase, Staphylococcus aureus CstA.

Biochemistry - 14 Apr 2015

Higgins Khadine A, Peng Hui, Luebke Justin L, Chang Feng-Ming James, Giedroc David P

Abstract excerpt

The cst operon of the major human pathogen Staphylococcus aureus (S. aureus) is under the transcriptional control of CsoR-like sulfurtransferase repressor (CstR). Expression of this operon is induced by hydrogen sulfide, and two components of the cst operon, cstA and cstB, protect S. aureus from sulfide toxicity. CstA is a three-domain protein, and each domain harbors a single cysteine that is proposed to...

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PMID: 25793461
DOI: 10.1021/acs.biochem.5b00056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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