Article
Lack of association between angiotensin I-converting enzyme insertion/deletion gene functional polymorphism and panic disorder in humans.
Neuroscience letters - 3 Jun 2004
Shimizu Eiji, Hashimoto Kenji, Kobayashi Keisuke, Mitsumori Makoto, Ohgake Shintaro, Koizumi Hiroki, Okamura Naoe, Koike Kaori, Kumakiri Chikara, Nakazato Michiko, Komatsu Naoya, Iyo Masaomi
Abstract excerpt
Family and twin studies have indicated that genes influence susceptibility to panic disorder, but the genes involved remain unknown. The neuropeptide angiotensin II has been found to be involved in anxiety and regulation of respiration which are important in the pathophysiology of panic attacks. Assuming that angiotensins may be candidate genes in panic disorder, we analyzed the association between panic disorder...
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