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Article

Deletion allele of the ACE gene is not a risk factor for asthma predisposition.

Pneumologia (Bucharest, Romania) - 1 Jan 2000

Rad Isa Abdi, Bagheri Morteza, Rahimi-Rad Mohammad Hosein

Abstract excerpt

BACKGROUND: Angiotensin-converting enzyme (ACE) has an important role in inactivation of bradykinin and tachykinins which known as powerful bronchoconstrictors. It has been demonstrated that an insertion (1)/deletion (D) genetic variations within the ACE gene greatly influence the plasma level of ACE. OBJECTIVE: The aim of the present study was to determine the frequencies of ACE D and I alleles and ACE DD, DI...

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PMID: 22420170

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ACE

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