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Article

Association study of A2a adenosine receptor genetic polymorphism in panic disorder.

Neuroscience letters - 18 Apr 2005

Lam Pok, Hong Chen-Jee, Tsai Shih-Jen

Abstract excerpt

The adenosine A2a receptor (A2aAR) is thought to be implicated in the pathogenesis of panic disorder because caffeine, a potent antagonist for A2aAR, can precipitate panic attacks, and because disruption of the A2aAR gene increased anxiety-behaviors in mice. Recent studies demonstrated that the A2aAR 1976T > C genetic variant confers susceptibility to panic disorder though not by all studies. The present study...

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Identifiers

PMID: 15774265
DOI: 10.1016/j.neulet.2004.12.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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