Article
Insertion/deletion polymorphism in the gene for angiotensin converting enzyme (ACE) in panic disorder: A gender-specific effect?
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Feb 2010
Bandelow Borwin, Saleh Kristina, Pauls Jutta, Domschke Katharina, Wedekind Dirk, Falkai Peter
Abstract excerpt
Family, twin, and segregation analytic studies indicate a complex genetic contribution to panic disorder with an estimated heritability of 48%. Angiotensin-converting enzyme (ACE) degrades substance P, which has been implicated in anxiety-related behaviour. ACE has been suggested as a potential r...
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