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Article

New synaptic bouton formation is disrupted by misregulation of microtubule stability in aPKC mutants.

Neuron - 27 May 2004

Ruiz-Canada Catalina, Ashley James, Moeckel-Cole Stephanie, Drier Eric, Yin Jerry, Budnik Vivian

Abstract excerpt

The Baz/Par-3-Par-6-aPKC complex is an evolutionarily conserved cassette critical for the development of polarity in epithelial cells, neuroblasts, and oocytes. aPKC is also implicated in long-term synaptic plasticity in mammals and the persistence of memory in flies, suggesting a synaptic function for this cassette. Here we show that at Drosophila glutamatergic synapses, aPKC controls the formation and structure...

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Identifiers

PMID: 15157419
DOI: 10.1016/s0896-6273(04)00255-7
PMCID: PMC4656022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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