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Article

Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles.

Antimicrobial agents and chemotherapy - 1 Jun 2004

Chau Andrew S, Mendrick Cara A, Sabatelli Frank J, Loebenberg David, McNicholas Paul M

Abstract excerpt

Real-time quantitative PCR was used to measure expression levels of genes encoding efflux pumps, ERG11 and two control genes, ACT1 and PMA1, in a collection of 14 fluconazole-susceptible Candida albicans isolates. For each gene, average expression levels and variations within the population were determined. These values were then used as reference points to make predictions about the molecular basis of resistance...

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Identifiers

PMID: 15155210
DOI: 10.1128/AAC.48.6.2124-2131.2004
PMCID: PMC415610

Genes

CDR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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