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Article

Genetic variation and mutational determinants of azole resistance in Candida albicans strains of oropharyngeal colonization in HIV patients and bloodstream infections.

Journal of biomedical science - 22 Feb 2026

Tsai Ming-Horng, Hsieh Chih-Hung, Tsai I-An, Chang Ching-Min, Chen Ting-Wen, Hsu Jen-Fu, Chu Shih-Ming, Huang Hsuan-Rong, Wang Shao-Hung, Lu Jang-Jih

Abstract excerpt

OBJECTIVES: We aimed to analyze the genomic variations associated with high azole resistance in the C. albicans isolates of intensive care unit (ICU) patients with Candida bloodstream infections (BSIs) and those from oropharyngeal colonization in HIV patients. METHODS: The genomic DNA of azole-resistant C. albicans isolates was analyzed using the Oxford Nanopore platform. Subsequent analyses included ERG11...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41724950
DOI: 10.1186/s12929-026-01231-4
PMCID: PMC12925357

Genes

CDR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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