Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Haplotype analysis of the folate-related genes MTHFR, MTRR, and MTR and migraine with aura.

Cephalalgia : an international journal of headache - 1 May 2013

Roecklein Kathryn A, Scher Ann I, Smith Albert, Harris Tamara, Eiriksdottir Gudny, Garcia Melissa, Gudnason Villi, Launer Lenore J

Abstract excerpt

AIMS: The C677T variant in the methylenetetrahydrofolate reductase ( MTHFR ; EC 1.5.1.20) enzyme, a key player in the folate metabolic pathway, has been associated with increased risk of migraine with aura. Other genes encoding molecular components of this pathway include methionine synthase ( MTR ; EC 2.1.1.13) and methionine synthase reductase ( MTRR ; EC 2.1.1.135) among others. We performed a haplotype...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Ferredoxin-NADP Reductase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Folic Acid

Share to Genetic Association Studies

Share to Haplotypes

Share to Iceland

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Migraine with Aura

Source

Open in PubMed Open full text

Identifiers

PMID: 23430981
DOI: 10.1177/0333102413477738
PMCID: PMC4231882

Genes

MTRR
MTHFR
MTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Haplotype analysis of the folate-related genes MTHFR, MTRR, and MTR and migraine with aura.PMID 23430981Read ↗

Association study of MTHFD1 coding polymorphisms R134K and R653Q with migraine susceptibility.Semantic proximity Read ↗

The role of the MTHFR gene in migraine.Semantic proximity Read ↗

The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura.Semantic proximity Read ↗

Migraine and MTHFR C677T genotype in a population-based sample.Semantic proximity Read ↗

MTHFR T677 Homozygosis Influences the Presence of Aura in MigraineursSemantic proximity Read ↗

Association of the C677T and A1298C polymorphisms in the 5,10 methylenetetrahydrofolate reductase gene in patients with migraine risk.Semantic proximity Read ↗

Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular disease.Semantic proximity Read ↗

Targeting MTHFR for the treatment of migrainesSemantic proximity Read ↗

Association of MTHFR gene polymorphisms with migraine in North Indian population.Semantic proximity Read ↗

Relation between Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Migraine SusceptibilitySemantic proximity Read ↗

Genotypes of the MTHFR C677T and MTRR A66G genes act independently to reduce migraine disability in response to vitamin supplementation.Semantic proximity Read ↗

Genetics of migraine aura: an update.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.