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Article

Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewal

20 May 2004

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Share to Acute Myeloid Leukemia Research
Share to Hematopoietic Stem Cell Transplantation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 15152269
DOI: 10.1038/sj.leu.2403396

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Related research

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Expression of AML1-ETO in human myelomonocytic cells selectively inhibits granulocytic differentiation and promotes their self-renewalPMID 15152269Read ↗

The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cellsSemantic proximity Read ↗

RUNX1 mutations enhance self-renewal and block granulocytic differentiation in human in vitro models and primary AMLsSemantic proximity Read ↗

AML1/ETO induces self-renewal in hematopoietic progenitor cells via the Groucho-related amino-terminal AES proteinSemantic proximity Read ↗

Single-cell dissection reveals promotive role of ENO1 in leukemia stem cell self-renewal and chemoresistance in acute myeloid leukemiaSemantic proximity Read ↗

Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic elementSemantic proximity Read ↗

The AML1-ETO fusion gene promotes extensive self-renewal of human primary erythroid cellsSemantic proximity Read ↗

Increased expression of RUNX3 inhibits normal human myeloid developmentSemantic proximity Read ↗

Overexpression of Ets-1 in human hematopoietic progenitor cells blocks erythroid and promotes megakaryocytic differentiationSemantic proximity Read ↗

Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid LeukemiaSemantic proximity Read ↗

Leukemic stem cells hijack lineage inappropriate signalling pathways to promote their growthSemantic proximity Read ↗

AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocationSemantic proximity Read ↗

AML1-ETO meets JAK2: clinical evidence for the two hit model of leukemogenesis from a myeloproliferative syndrome progressing to acute myeloid leukemia.Semantic proximity Read ↗

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