Clinical and molecular characterization of patients with heterozygous mutations in wilms tumor suppressor gene 1.

doi:10.2215/CJN.10141014

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Clinical and molecular characterization of patients with heterozygous mutations in wilms tumor suppressor gene 1.

Clinical journal of the American Society of Nephrology : CJASN - 7 May 2015

Lehnhardt Anja, Karnatz Claartje, Ahlenstiel-Grunow Thurid, Benz Kerstin, Benz Marcus R, Budde Klemens, Büscher Anja K, Fehr Thomas, Feldkötter Markus, Graf Norbert, Höcker Britta, Jungraithmayr Therese, Klaus Günter, Koehler Birgit, Konrad Martin, Kranz Birgitta, Montoya Carmen R, Müller Dominik, Neuhaus Thomas J, Oh Jun, Pape Lars, Pohl Martin, Royer-Pokora Brigitte, Querfeld Uwe, Schneppenheim Reinhard, Staude Hagen, Spartà Giuseppina, Timmermann Kirsten, Wilkening Frauke, Wygoda Simone, Bergmann Carsten, Kemper Markus J

Abstract excerpt

BACKGROUND AND OBJECTIVES: The Wilms tumor suppressor gene 1 (WT1) plays an essential role in urogenital and kidney development. Genotype/phenotype correlations of WT1 mutations with renal function and proteinuria have been observed in world-wide cohorts with nephrotic syndrome or Wilms tumor (WT). This study analyzed mid-European patients with known constitutional heterozygous mutations in WT1, including...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Austria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Wilms Tumor

Share to Nephrectomy

Share to Proteinuria

Share to Renal Dialysis

Share to Switzerland

Share to Urogenital Abnormalities

Share to Wilms Tumor

Source

Open in PubMed Open full text

Identifiers

PMID: 25818337
DOI: 10.2215/CJN.10141014
PMCID: PMC4422247

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical and molecular characterization of patients with heterozygous mutations in wilms tumor suppressor gene 1.PMID 25818337Read ↗

Clinical Characterization of a National Cohort of Patients With Germline WT1 Variants Including Late-Onset PhenotypesSemantic proximity Read ↗

Spectrum of Clinical Manifestations in Children With WT1 Mutation: Case Series and Literature ReviewSemantic proximity Read ↗

Genotype-phenotype analysis of pediatric patients with WT1 glomerulopathy.Semantic proximity Read ↗

The genetic factors contributing to the development of Wilm's tumor and their clinical utility in its diagnosis and prognosis.Semantic proximity Read ↗

WT1 Pathogenic Variants are Associated with a Broad Spectrum of Differences in Sex Development Phenotypes and Heterogeneous Progression of Renal Disease.Semantic proximity Read ↗

Long-term kidney function in children with Wilms tumour and constitutional WT1 pathogenic variant.Semantic proximity Read ↗

Genotype/phenotype correlation in nephrotic syndrome caused by WT1 mutations.Semantic proximity Read ↗

Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development.Semantic proximity Read ↗

Exploring the Multifaceted Role of WT1 in Kidney Development and DiseaseSemantic proximity Read ↗

Genotype-phenotype associations in WT1 glomerulopathy.Semantic proximity Read ↗

Wilms TumorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.