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Article

The Booroola (FecB) mutation is associated with smaller adrenal glands in young adult ewes.

Reproductive biomedicine online - 1 Apr 2004

Souza C J H, Baird D T

Abstract excerpt

The Booroola (FecB) phenotype is associated with a mutation in the bone morphogenetic protein (BMP) receptor 1B. The BMP action is important during development; surprisingly the only differences so far observed in adult animals are restricted to the ovaries where precocious development of the antral follicles and increased ovulation rate of mutant ewes is observed. The internal organs of 17 ewes homozygous for...

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Source

Identifiers

PMID: 15149564
DOI: 10.1016/s1472-6483(10)60925-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Booroola (FecB) mutation is associated with smaller adrenal glands in young adult ewes.PMID 15149564Read ↗

The Booroola mutation in sheep is associated with an alteration of the bone morphogenetic protein receptor-IB functionality.Semantic proximity Read ↗

Bone morphogenetic proteins and folliculogenesis: lessons from the Booroola mutation.Semantic proximity Read ↗

The Booroola (FecB) phenotype is associated with a mutation in the bone morphogenetic receptor type 1 B (BMPR1B) gene.Semantic proximity Read ↗

Effects of the Booroola gene (FecB) on body weight, ovarian development and hormone concentrations during fetal life.Semantic proximity Read ↗

Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Mérino ewes.Semantic proximity Read ↗

Booroola BMPR1B mutation alters early follicular development and oocyte ultrastructure in sheep.Semantic proximity Read ↗

Mechanisms of action of the principal prolific genes and their application to sheep production.Semantic proximity Read ↗

Enhanced response of granulosa and theca cells from sheep carriers of the FecB mutation in vitro to gonadotropins and bone morphogenic protein-2, -4, and -6.Semantic proximity Read ↗

Highly prolific Booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor (ALK-6) that is expressed in both oocytes and granulosa cells.Semantic proximity Read ↗

Ontogeny of ovarian follicle development in Booroola sheep fetuses that are homozygous carriers or non-carriers of the FecB gene.Semantic proximity Read ↗

Ovarian follicle development in Booroola sheep exhibiting impaired bone morphogenetic protein signalling pathway.Semantic proximity Read ↗

Integration analysis of pituitary proteome and transcriptome reveals fertility-related biomarkers in FecB mutant Small Tail Han sheep.Semantic proximity Read ↗

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