Article
Booroola BMPR1B mutation alters early follicular development and oocyte ultrastructure in sheep.
Reproduction, fertility, and development - 1 Jan 2012
Reader Karen L, Haydon Lisa J, Littlejohn Roger P, Juengel Jennifer L, McNatty Kenneth P
Abstract excerpt
Booroola ewes homozygous (BB) for a mutation in the bone morphogenetic protein receptor-1b (BMPR1B) gene exhibit higher ovulation rates, have larger diameter oocytes at earlier stages of follicular development (i.e. Type 3) and smaller diameter follicles at ovulation than wild-type (++) sheep. However, it is not known when BMPR1B is first expressed in the developing ovary or the cell types involved. In addition,...
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