Article
Ovarian follicle development in Booroola sheep exhibiting impaired bone morphogenetic protein signalling pathway.
Reproduction (Cambridge, England) - 1 Oct 2009
Ruoss Chantelle, Tadros Amanda, O'Shea Tim, McFarlane Jim, Almahbobi Ghanim
Abstract excerpt
The role of bone morphogenetic proteins (BMPs) in the regulation of ovarian function has been extensively investigated but the mechanism of regulation is not well understood. The aim of this study was to investigate the effect of mutation in the BMP receptor in Booroola sheep on the number of primordial follicles and rate of follicle recruitment in comparison with that in normal merino sheep in vivo. Whole sheep...
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