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Article

The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1.

Proceedings of the National Academy of Sciences of the United States of America - 25 May 2004

Xie Kefang, Sowden Mark P, Dance Geoffrey S C, Torelli Andrew T, Smith Harold C, Wedekind Joseph E

Abstract excerpt

Activation-induced deaminase (AID) uses base deamination for class-switch recombination and somatic hypermutation and is related to the mammalian RNA-editing enzyme apolipoprotein B editing catalytic subunit 1 (APOBEC-1). CDD1 is a yeast ortholog of APOBEC-1 that exhibits cytidine deaminase and RNA-editing activity. Here, we present the crystal structure of CDD1 at 2.0-A resolution and its use in comparative...

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Share to AICDA (Activation-Induced Cytidine Deaminase)
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15148397
DOI: 10.1073/pnas.0400493101
PMCID: PMC419566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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