Roles of Hroth, the ascidian otx gene, in the differentiation of the brain (sensory vesicle) and anterior trunk epidermis in the larval development of Halocynthia roretzi.

doi:10.1016/j.mod.2004.03.017

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Article

Roles of Hroth, the ascidian otx gene, in the differentiation of the brain (sensory vesicle) and anterior trunk epidermis in the larval development of Halocynthia roretzi.

Mechanisms of development - 1 May 2004

Wada Shuichi, Sudou Norihiro, Saiga Hidetoshi

Abstract excerpt

Otx genes are expressed in the anterior neural tube and endoderm in all of the chordates so far examined. In mouse embryos, important roles of otx genes in the brain development have been well documented. However, roles of otx genes in other chordate species have been less characterized. To advance our understanding about roles of otx genes in chordates, we have studied Hroth, otx of the ascidian, Halocynthia...

Topics

Animals
Animals, Genetically Modified
Body Patterning
Brain
Cell Differentiation
Embryo, Nonmammalian
Epidermal Cells
Epidermis
Gene Deletion
Gene Expression Regulation, Developmental
Homeodomain Proteins
In Situ Hybridization
Larva
Oligonucleotides, Antisense

Source

Open in PubMed

Identifiers

PMID: 15147764
DOI: 10.1016/j.mod.2004.03.017

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Otx Transcription Factors

Phenotype

Protein Biosynthesis

RNA, Messenger