Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HrzicN, a new Zic family gene of ascidians, plays essential roles in the neural tube and notochord development.

Development (Cambridge, England) - 1 Dec 2002

Wada Shuichi, Saiga Hidetoshi

Abstract excerpt

Two axial structures, a neural tube and a notochord, are key structures in the chordate body plan and in understanding the origin of chordates. To expand our knowledge on mechanisms of development of the neural tube in lower chordates, we have undertaken isolation and characterization of HrzicN, a new member of the Zic family gene of the ascidian, Halocynthia roretzi. HrzicN expression was detected by whole-mount...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Fibroblast Growth Factors
Share to Mesoderm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscles

Share to Neural Crest

Share to Notochord

Share to Oligonucleotides

Share to Urochordata

Source

Identifiers

PMID: 12421701
DOI: 10.1242/dev.00156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HrzicN, a new Zic family gene of ascidians, plays essential roles in the neural tube and notochord development.PMID 12421701Read ↗

Notch signaling is involved in nervous system formation in ascidian embryos.Semantic proximity Read ↗

Roles of Hroth, the ascidian otx gene, in the differentiation of the brain (sensory vesicle) and anterior trunk epidermis in the larval development of Halocynthia roretzi.Semantic proximity Read ↗

Functional analysis of an ascidian homologue of vertebrate Bmp-2/Bmp-4 suggests its role in the inhibition of neural fate specification.Semantic proximity Read ↗

Vegetal cell fate specification and anterior neuroectoderm formation by Hroth, the ascidian homologue of orthodenticle/otx.Semantic proximity Read ↗

Expression of the labial group Hox gene HrHox-1 and its alteration induced by retinoic acid in development of the ascidian Halocynthia roretzi.Semantic proximity Read ↗

Ascidian otx gene Hroth activates transcription of the brain-specific gene HrTRP.Semantic proximity Read ↗

Evolutionary alterations of the minimal promoter for notochord-specific Brachyury expression in ascidian embryos.Semantic proximity Read ↗

Tbx2/3 is an essential mediator within the Brachyury gene network during Ciona notochord development.Semantic proximity Read ↗

Zebrafish Zic2a and Zic2b regulate neural crest and craniofacial development.Semantic proximity Read ↗

Expression of snail2, a second member of the zebrafish snail family, in cephalic mesendoderm and presumptive neural crest of wild-type and spadetail mutant embryos.Semantic proximity Read ↗

Zebrafish R-cadherin (Cdh4) controls visual system development and differentiation.Semantic proximity Read ↗

An ancient chordin-like gene in organizer formation of Hydra.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.