Article
Notch signaling is involved in nervous system formation in ascidian embryos.
Development genes and evolution - 1 Nov 2002
Akanuma Takashi, Hori Sawako, Darras Sébastien, Nishida Hiroki
Abstract excerpt
Notch signaling plays crucial roles during embryogenesis in various metazoans. HrNotch, a Notch homologue in the ascidian Halocynthia roretzi, has been previously cloned, and its expression pattern suggests that HrNotch signaling is involved in nervous system formation. To determine the function of HrNotch signaling, in the present study we examined the effects of the constitutively activated forms of HrNotch....
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