[Physiology of somatotropic axis: interest of gene inactivation experiments].

Abstract excerpt

Research into the somatotropic axis (growth hormone, insulin-like growth factors) has received renewed attention in the last few years, owing to techniques for genetic modification in the mouse, essentially transgenesis, and gene inactivation. The results, compared with phenotypic and molecular data for various pathological conditions, e.g. short stature, have increased our understanding of the function of the...

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