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Article

The hormonal action of IGF1 in postnatal mouse growth.

Proceedings of the National Academy of Sciences of the United States of America - 9 Dec 2008

Stratikopoulos Elias, Szabolcs Matthias, Dragatsis Ioannis, Klinakis Apostolos, Efstratiadis Argiris

Abstract excerpt

The mammalian insulin-like growth factor 1 (IGF1), which is a member of a major growth-promoting signaling system, is produced by many tissues and functions throughout embryonic and postnatal development in an autocrine/paracrine fashion. In addition to this local action, IGF1 secreted by the liver and circulating in the plasma presumably acts systemically as a classical hormone. However, an endocrine role of...

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Identifiers

PMID: 19033454
DOI: 10.1073/pnas.0809223105
PMCID: PMC2614769

Genes

IGF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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