Article

The Somatomedin Hypothesis: 2001

2001-02-01

Abstract excerpt

Since the original somatomedin hypothesis was conceived, a number of important discoveries have allowed investigators to modify the concept. Originally somatic growth was thought to be controlled by pituitary GH and mediated by circulating insulin-like growth factor-I (IGF-I, somatomedin C) expressed exclusively by the liver. With the discovery that IGF-I is produced by most, if not all, tissues, the role of autoc...

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Growth Hormone and Insulin-like Growth Factors

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Literature Corpus work: 766d97af-1245-5893-b585-91f087496d64
DOI: 10.1210/er.22.1.53

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