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Article

Tamoxifen induces the expression of maspin through estrogen receptor-alpha.

Cancer letters - 8 Jun 2004

Liu Zesheng, Shi Heidi Y, Nawaz Zafar, Zhang Ming

Abstract excerpt

Maspin (mammary serine protease inhibitor) is a tumor suppressor gene that plays an important role in inhibiting tumor growth, invasion and metastasis. Maspin expression is down regulated at transcription level in primary and metastatic breast tumor cells. Previous studies on hormonal regulation of maspin prompt us to test whether an estrogen antagonist tamoxifen (TAM) can exert its anti-tumor function by up...

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Identifiers

PMID: 15145521
DOI: 10.1016/j.canlet.2003.11.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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