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Article

Polymorphism in NOD2, Crohn's disease, and susceptibility to pulmonary tuberculosis.

FEMS immunology and medical microbiology - 1 Jun 2004

Stockton Jemima C, Howson Joanna M M, Awomoyi Agnes A, McAdam Keith P, Blackwell Jenefer M, Newport Melanie J

Abstract excerpt

The nucleotide oligomerization binding domain 2 gene (NOD2) encodes an intracellular receptor for bacterial components, which is expressed in monocytes and is associated with Crohn's Disease (CD). This finding, along with epidemiological evidence, supports a role for infection in the pathogenesis of CD. Speculation that mycobacteria are involved in CD led us to investigate NOD2 in susceptibility to tuberculosis...

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Source

Identifiers

PMID: 15145460
DOI: 10.1016/j.femsim.2004.02.004

Genes

NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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