Article
Tight junction protein Par6 interacts with an evolutionarily conserved region in the amino terminus of PALS1/stardust.
The Journal of biological chemistry - 16 Jul 2004
Wang Qian, Hurd Toby W, Margolis Ben
Abstract excerpt
Tight junctions are the structures in mammalian epithelial cells that separate the apical and basolateral membranes and may also be important in the establishment of cell polarity. Two evolutionarily conserved multiprotein complexes, Crumbs-PALS1 (Stardust)-PATJ and Cdc42-Par6-Par3-atypical protein kinase C, have been implicated in the assembly of tight junctions and in polarization of Drosophila melanogaster...
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