Article
Drosophila Patj plays a supporting role in apical-basal polarity but is essential for viability.
Development (Cambridge, England) - 1 Aug 2012
Zhou Wenke, Hong Yang
Abstract excerpt
Patj has been characterized as one of the so-called polarity proteins that play essential and conserved roles in regulating cell polarity in many different cell types. Studies of Drosophila and mammalian cells suggest that Patj is required for the apical polarity protein complex Crumbs-Stardust (Pals1 or Mpp5 in mammalian cells) to establish apical-basal polarity. However, owing to the lack of suitable genetic...
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