Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Osteopontin—A Master Regulator of Epithelial-Mesenchymal Transition

23 Mar 2016

Abstract excerpt

Osteopontin (OPN) plays an important functional role in both physiologic and pathologic states. OPN is implicated in the progression of fibrosis, cancer, and metastatic disease in several organ systems. The epithelial-mesenchymal transition (EMT), first described in embryology, is increasingly being recognized as a significant contributor to fibrotic phenotypes and tumor progression. Several well-established...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Dental Protein Studies
Share to Cancer Cells and Metastasis
Share to Digestive system and related health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27023622
DOI: 10.3390/jcm5040039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Osteopontin—A Master Regulator of Epithelial-Mesenchymal TransitionPMID 27023622Read ↗

Osteopontin up-regulates critical epithelial-mesenchymal transition transcription factors to induce an aggressive breast cancer phenotype.Semantic proximity Read ↗

Role of osteopontin in the pathophysiology of cancerSemantic proximity Read ↗

Osteopontin Splicing Isoforms Contribute to Endometriotic Proliferation, Migration, and Epithelial-Mesenchymal Transition in Endometrial Epithelial CellsSemantic proximity Read ↗

Epithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunitiesSemantic proximity Read ↗

The role of epithelial&ndash;mesenchymal transition programming in invasion and metastasis: a clinical perspectiveSemantic proximity Read ↗

The role of Osteopontin in tumor metastasis.Semantic proximity Read ↗

Multilayer control of the EMT master regulators.Semantic proximity Read ↗

Osteopontin induces multiple changes in gene expression that reflect the six “hallmarks of cancer” in a model of breast cancer progressionSemantic proximity Read ↗

Role of osteopontin in cellular signaling and metastatic phenotype.Semantic proximity Read ↗

Osteopontin: role in cell signaling and cancer progressionSemantic proximity Read ↗

Epithelial-mesenchymal transition and its transcription factors.Semantic proximity Read ↗

Shake It Up Baby Now: The Changing Focus on TWIST1 and Epithelial to Mesenchymal Transition in Cancer and Other DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.