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Article

An iron-sulfur cluster domain in Elp3 important for the structural integrity of elongator.

The Journal of biological chemistry - 2 Jan 2009

Greenwood Catherine, Selth Luke A, Dirac-Svejstrup A Barbara, Svejstrup Jesper Q

Abstract excerpt

The Elongator complex functions in diverse cellular processes, such as RNA polymerase II transcription and tRNA modification. The Elp3 subunit possesses a C-terminal histone acetyltransferase (HAT) domain and an N-terminal sequence that resembles an iron-sulfur (FeS) cluster motif. The HAT domain is well characterized, but the role of the FeS cluster is unknown, although one report proposed that it might be...

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PMID: 18986986
DOI: 10.1074/jbc.M805312200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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