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Article

Overlapping roles for the histone acetyltransferase activities of SAGA and elongator in vivo.

The EMBO journal - 15 Jun 2000

Wittschieben B O, Fellows J, Du W, Stillman D J, Svejstrup J Q

Abstract excerpt

Elp3 and Gcn5 are histone acetyltransferases (HATs) that function in transcription as subunits of Elongator and SAGA/ADA, respectively. Here we show that mutations that impair the in vitro HAT activity of Elp3 confer typical elp phenotypes such as temperature sensitivity. Combining an elp3Delta m...

Topics

Acetylation
Acetyltransferases
Chromatin
DNA-Binding Proteins
Fungal Proteins
Histone Acetyltransferases
Histone Deacetylases
Mutation
Phenotype
Protein Kinases
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

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Identifiers

PMID: 10856249
DOI: 10.1093/emboj/19.12.3060
PMCID: PMC203375

Genes

ADA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10856249-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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Overlapping roles for the histone acetyltransferase activities of SAGA and elongator in vivo.PMID 10856249Read ↗

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