Article
RNA polymerase II elongator holoenzyme is composed of two discrete subcomplexes.
The Journal of biological chemistry - 31 Aug 2001
Winkler G S, Petrakis T G, Ethelberg S, Tokunaga M, Erdjument-Bromage H, Tempst P, Svejstrup J Q
Abstract excerpt
Elongator is a histone acetyltransferase complex that associates with the elongating form of RNA polymerase II. We purified Elongator to virtual homogeneity via a rapid three-step procedure based largely on affinity chromatography. The purified factor, holo-Elongator, is a labile six-subunit factor composed of two discrete subcomplexes: one comprised of the previously identified Elp1, Elp2, and Elp3 proteins and...
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