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Article

Equine estrogen metabolite 4-hydroxyequilenin induces anchorage-independent growth of human mammary epithelial MCF-10A cells: differential gene expression.

Mutation research - 4 Jun 2004

Cuendet Muriel, Liu Xuemei, Pisha Emily, Li Yan, Yao Jiaqin, Yu Linning, Bolton Judy L

Abstract excerpt

Long-term exposure to synthetic and endogenous estrogens has been associated with the development of cancer in several tissues. One potential mechanism of estrogen carcinogenesis involves catechol formation and these catechols are further oxidized to electrophilic/redox active o-quinones, which have the potential to both initiate and promote the carcinogenic process. Previously we showed that 4-hydroxyequilenin...

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Identifiers

PMID: 15135645
DOI: 10.1016/j.mrfmmm.2004.02.005

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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