Article
[Cutaneous drug reactions: pharmacogenetic news].
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie - 1 May 2004
Buffard V, Roujeau J-C
Abstract excerpt
Identifying genetic factors in severe drug eruption should improve efficacy and safety of drug prescription. The first pharmacogenetic studies concerned the polymorphism of genes encoding drug metabolism enzymes (especially for sulfamides reactions in AIDS and anticonvulsants reactions). Recent studies did not confirm the role of genotypic variation in metabolism enzymes in drug reaction. Genes controlling immune...
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