Article
Asialoerythropoietin is not effective in the R6/2 line of Huntington's disease mice.
BMC neuroscience - 10 May 2004
Gil Joana M A C, Leist Marcel, Popovic Natalija, Brundin Patrik, Petersén Asa
Abstract excerpt
BACKGROUND: Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by an expanded CAG repeat in the HD gene. Both excitotoxicity and oxidative stress have been proposed to play important roles in the pathogenesis of HD. Since no effective treatment is available, this study was designed to explore the therapeutic potential of erythropoietin (EPO), a cytokine that has been found to prevent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
