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Article

Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease.

BMC neuroscience - 13 Sept 2010

Kohl Zacharias, Regensburger Martin, Aigner Robert, Kandasamy Mahesh, Winner Beate, Aigner Ludwig, Winkler Jürgen

Abstract excerpt

BACKGROUND: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder linked to expanded CAG-triplet nucleotide repeats within the huntingtin gene. Intracellular huntingtin aggregates are present in neurons of distinct brain areas, among them regions of adult neurogenesis incl...

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Identifiers

PMID: 20836877
DOI: 10.1186/1471-2202-11-114
PMCID: PMC2945356

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20836877-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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