Article
Nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase
1 May 2004
Abstract excerpt
The development of novel compounds that can effectively inhibit both wild type and the most consensus resistant strains of human immunodeficiency virus type 1 (HIV-1) is the primary focus in HIV disease management. Combination therapy, comprising at least three classes of drugs, has become the standard of care for acquired immunodeficiency syndrome (AIDS) or HIV-infected individuals. The drug cocktail can...
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