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Article

Nucleoside and nucleotide inhibitors of HIV-1 replication.

Cellular and molecular life sciences : CMLS - 1 Jan 2006

Vivet-Boudou V, Didierjean J, Isel C, Marquet R

Abstract excerpt

HIV-1 reverse transcriptase (RT) is one of the main targets for antiviral therapy. Two classes of RT inhibitors can be distinguished: those that are nucleoside or nucleotide analogues (sharing the common NRTIs abbreviation) and those that are not. This review focuses on the NRTIs, which are highly efficient in slowing down viral replication and are used in combination regimens. Unfortunately, the current...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16389458
DOI: 10.1007/s00018-005-5367-x
PMCID: PMC11136153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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