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Article

Divergent functions of murine Pax3 and Pax7 in limb muscle development.

Genes & development - 1 May 2004

Relaix Frédéric, Rocancourt Didier, Mansouri Ahmed, Buckingham Margaret

Abstract excerpt

Pax genes encode evolutionarily conserved transcription factors that play critical roles in development. Pax3 and Pax7 constitute one of the four Pax subfamilies. Despite partially overlapping expression domains, mouse mutations for Pax3 and Pax7 have very different consequences. To investigate the mechanism of these contrasting phenotypes, we replaced Pax3 by Pax7 by using gene targeting in the mouse. Pax7 can...

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Source

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Identifiers

PMID: 15132998
DOI: 10.1101/gad.301004
PMCID: PMC406297

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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