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Article

The nucleolar Net1/Cfi1-related protein Dnt1 antagonizes the septation initiation network in fission yeast.

Molecular biology of the cell - 1 Aug 2007

Jin Quan-Wen, Ray Samriddha, Choi Sung Hugh, McCollum Dannel

Abstract excerpt

The septation initiation network (SIN) and mitotic exit network (MEN) signaling pathways regulate cytokinesis and mitotic exit in the yeasts Schizosaccharomyces pombe, and Saccharomyces cerevisiae, respectively. One function of these pathways is to keep the Cdc14-family phosphatase, called Clp1 in S. pombe, from being sequestered and inhibited in the nucleolus. In S. pombe, the SIN and Clp1 act as part of a...

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Identifiers

PMID: 17538026
DOI: 10.1091/mbc.e06-09-0853
PMCID: PMC1949376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

The nucleolar Net1/Cfi1-related protein Dnt1 antagonizes the septation initiation network in fission yeast.PMID 17538026Read ↗

The SIN kinase Sid2 regulates cytoplasmic retention of the S. pombe Cdc14-like phosphatase Clp1.Semantic proximity Read ↗

Dma1 prevents mitotic exit and cytokinesis by inhibiting the septation initiation network (SIN).Semantic proximity Read ↗

Dnt1 acts as a mitotic inhibitor of the spindle checkpoint protein dma1 in fission yeast.Semantic proximity Read ↗

Etd1p is a novel protein that links the SIN cascade with cytokinesis.Semantic proximity Read ↗

Saccharomyces cerevisiae Mob1p is required for cytokinesis and mitotic exit.Semantic proximity Read ↗

Nuc2p, a subunit of the anaphase-promoting complex, inhibits septation initiation network following cytokinesis in fission yeast.Semantic proximity Read ↗

IQGAP and mitotic exit network (MEN) proteins are required for cytokinesis and re-polarization of the actin cytoskeleton in the budding yeast, Saccharomyces cerevisiae.Semantic proximity Read ↗

S. pombe cdc11p, together with sid4p, provides an anchor for septation initiation network proteins on the spindle pole body.Semantic proximity Read ↗

The S. pombe cytokinesis NDR kinase Sid2 activates Fin1 NIMA kinase to control mitotic commitment through Pom1/Wee1.Semantic proximity Read ↗

Mutations affecting spindle pole body and mitotic exit network function are synthetically lethal with a deletion of the nucleoporin NUP1 in S. cerevisiae.Semantic proximity Read ↗

Crm1-mediated nuclear export of Cdc14 is required for the completion of cytokinesis in budding yeast.Semantic proximity Read ↗

Bni5p, a septin-interacting protein, is required for normal septin function and cytokinesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

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