Article
The nieuwkoid/dharma homeobox gene is essential for bmp2b repression in the zebrafish pregastrula.
Developmental biology - 15 Nov 1999
Koos D S, Ho R K
Abstract excerpt
Dorsoventral specification of the zebrafish gastrula is governed by the functions of the dorsal shield, a region of the embryo functionally analogous to the amphibian Spemann organizer. We report that the bozozok locus encodes the transcription factor nieuwkoid/dharma, a homeobox gene with non-cell-autonomous organizer-inducing activity. The nieuwkoid/dharma gene is expressed prior to the onset of gastrulation in...
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