Article
Cohesin-dependent regulation of Runx genes.
Development (Cambridge, England) - 1 Jul 2007
Horsfield Julia A, Anagnostou Sasha H, Hu Jimmy Kuang-Hsien, Cho Kitty Hsiao Yu, Geisler Robert, Lieschke Graham, Crosier Kathryn E, Crosier Philip S
Abstract excerpt
Runx transcription factors determine cell fate in many lineages. Maintaining balanced levels of Runx proteins is crucial, as deregulated expression leads to cancers and developmental disorders. We conducted a forward genetic screen in zebrafish for positive regulators of runx1 that yielded the co...
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