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Article

Parallel Synthesis and Antimalarial Screening of a 4-Aminoquinoline Library

15 Apr 2004

Abstract excerpt

Due to growing problems with drug resistance, there is an outstanding need for new, cost-effective drugs for the treatment of malaria. The 4-aminoquinolines have provided a number of useful antimalarials, and Plasmodium falciparum, the causative organism for the most deadly form of human malaria, is generally slow to develop resistance to these drugs. Therefore, diverse screening libraries of quinolines continue...

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Identifiers

PMID: 15132606
DOI: 10.1021/cc0340473

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Source receipt: pubmed, retrieved 7 Sept 2026.

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