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Article

Cancer variation associated with the position of the mutation in the BRCA2 gene.

Familial cancer - 1 Jan 2004

Lubinski Jan, Phelan Catherine M, Ghadirian Parviz, Lynch Henry T, Garber Judy, Weber Barbara, Tung Nadine, Horsman Douglas, Isaacs Claudine, Monteiro Alvaro N A, Sun Ping, Narod Steven A

Abstract excerpt

Inherited mutations of the BRCA2 gene give rise to a multi-site cancer phenotype which includes breast cancer (in female and males), ovarian, pancreatic and prostate cancer, ocular and other melanomas, laryngeal, colon and stomach cancers. Interpretation of test results and risk assessment is therefore complex. It has been proposed that families with mutations in the ovarian cancer cluster region (OCCR) of exon...

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Source

Identifiers

PMID: 15131399
DOI: 10.1023/B:FAME.0000026816.32400.45

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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