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Ovarian cancer in BRCA1/2 mutation carriers: The impact of mutation position and family history on the cancer risk.

Maturitas - 1 Oct 2015

Teixeira Natalia, Mourits Marian J E, Vos Janet R, Kolk Dorina M van der, Jansen Liesbeth, Oosterwijk Jan C, Bock Geertruida H de

Abstract excerpt

OBJECTIVES: Assessing the combined impact of mutation position, regarding the ovarian cancer cluster region (OCCR), and type of cancer family history (FH) on age-related penetrance of ovarian cancer (OC) in women from BRCA1/2 families from the northern Netherlands. STUDY DESIGN: A consecutive series of 1763 mutation carriers and their first-degree relatives from 355 proven BRCA1/2 families with a history of...

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Identifiers

PMID: 26239500
DOI: 10.1016/j.maturitas.2015.07.001

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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