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Article

Genotype in BRCA-associated breast cancers.

The breast journal - 1 Jan 2000

Meric-Bernstam Funda, Gutierrez-Barrera Angelica M, Litton Jennifer, Mellor-Crummey Lauren, Ready Kaylene, Gonzalez-Angulo Ana Maria, Lu Karen H, Hortobagyi Gabriel N, Arun Banu K

Abstract excerpt

Women with BRCA1 or 2 mutations are at high risk for breast cancer. For BRCA1, a trend of increasing risk has been associated with increasing downstream (3') location for mutations compared to the upstream (5') mutations in the gene. For BRCA2, an increased risk of breast cancer has been associated with mutations outside of the ovarian cancer cluster region (OCCR). We sought to determine the mutation position in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23231005
DOI: 10.1111/tbj.12056
PMCID: PMC4437798

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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