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Article

Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance.

Genome biology - 1 Jan 2004

Miller Lance D, McPhie Peter, Suzuki Hideyo, Kato Yasuhito, Liu Edison T, Cheng Sheue-yann

Abstract excerpt

BACKGROUND: Resistance to thyroid hormone (RTH) is caused by mutations of the thyroid hormone receptor beta (TRbeta) gene. To understand the transcriptional program underlying TRbeta mutant-induced phenotypic expression of RTH, cDNA microarrays were used to profile the expression of 11,500 genes in a mouse model of human RTH. RESULTS: We analyzed transcript levels in cerebellum, heart and white adipose tissue...

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Source

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Identifiers

PMID: 15128445
DOI: 10.1186/gb-2004-5-5-r31
PMCID: PMC416467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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