Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor Suppressor Maspin Is Up-Regulated during Keratinocyte Senescence, Exerting a Paracrine Antiangiogenic Activity

1 May 2004

Abstract excerpt

Cell senescence is a physiological program of terminal growth arrest, which is believed to play an important role in cancer prevention. Senescent cells secrete multiple growth-regulatory proteins, some of which can affect tumor growth, survival, invasion, or angiogenesis. Changes in expression of different senescence-associated genes were analyzed in cultured human skin keratinocytes (KCs) that underwent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Corneal Surgery and Treatments
Share to Protease and Inhibitor Mechanisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15126325
DOI: 10.1158/0008-5472.can-03-2388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor Suppressor Maspin Is Up-Regulated during Keratinocyte Senescence, Exerting a Paracrine Antiangiogenic ActivityPMID 15126325Read ↗

Skin Cancer Microenvironment: What We Can Learn from Skin Aging?Semantic proximity Read ↗

The Senescence-Associated Secretory Phenotype: Critical Effector in Skin Cancer and Aging.Semantic proximity Read ↗

Cell Senescence-Independent Ageing of Human SkinSemantic proximity Read ↗

Unveiling senescence-associated secretory phenotype in epidermal aging: insights from reversibly immortalized keratinocytesSemantic proximity Read ↗

The serine protease inhibitor serpinB2 binds and stabilizes p21 in senescent cellsSemantic proximity Read ↗

Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells.Semantic proximity Read ↗

Cell Senescence-Independent Changes of Human Skin Fibroblasts with AgeSemantic proximity Read ↗

Secretion of Vascular Endothelial Growth Factor by Primary Human Fibroblasts at SenescenceSemantic proximity Read ↗

c-Myc is essential to prevent endothelial pro-inflammatory senescent phenotype.Semantic proximity Read ↗

Senescent Carcinoma-Associated Fibroblasts Upregulate IL8 to Enhance Prometastatic Phenotypes.Semantic proximity Read ↗

Chronic Resveratrol Treatment Reduces the Pro-angiogenic Effect of Human Fibroblast "Senescent-Associated Secretory Phenotype" on Endothelial Colony-Forming Cells: The Role of IL8.Semantic proximity Read ↗

p38MAPK Plays a Crucial Role in Stromal-Mediated TumorigenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.