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Article

c-Myc is essential to prevent endothelial pro-inflammatory senescent phenotype.

PloS one - 1 Jan 2013

Florea Victoria, Bhagavatula Nithya, Simovic Gordana, Macedo Francisco Y, Fock Ricardo A, Rodrigues Claudia O

Abstract excerpt

The proto-oncogene c-Myc is vital for vascular development and promotes tumor angiogenesis, but the mechanisms by which it controls blood vessel growth remain unclear. In the present work we investigated the effects of c-Myc knockdown in endothelial cell functions essential for angiogenesis to de...

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Identifiers

PMID: 24039874
DOI: 10.1371/journal.pone.0073146
PMCID: PMC3765198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24039874-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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