Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell Senescence-Independent Changes of Human Skin Fibroblasts with Age

9 Apr 2024

Abstract excerpt

Skin ageing is defined, in part, by collagen depletion and fragmentation that leads to a loss of mechanical tension. This is currently believed to reflect, in part, the accumulation of senescent cells. We compared the expression of genes and proteins for components of the extracellular matrix (ECM) as well as their regulators and found that in vitro senescent cells produced more matrix metalloproteinases (MMPs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Glycation End Products research
Share to Skin Protection and Aging
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38667274
DOI: 10.3390/cells13080659

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell Senescence-Independent Changes of Human Skin Fibroblasts with AgePMID 38667274Read ↗

Cell Senescence-Independent Ageing of Human SkinSemantic proximity Read ↗

Phenotypic and functional changes in dermal primary fibroblasts isolated from intrinsically aged human skin.Semantic proximity Read ↗

Skin aging from the perspective of dermal fibroblasts: the interplay between the adaptation to the extracellular matrix microenvironment and cell autonomous processesSemantic proximity Read ↗

The role of cellular senescence in skin aging and age-related skin pathologiesSemantic proximity Read ↗

Targeting Dermal Fibroblast Senescence: From Cellular Plasticity to Anti-Aging TherapiesSemantic proximity Read ↗

Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin.Semantic proximity Read ↗

Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin agingSemantic proximity Read ↗

The effect of aging in primary human dermal fibroblastsSemantic proximity Read ↗

Diminished and altered cellular senescence response in delayed wound healing of agingSemantic proximity Read ↗

Increase of fibrosis-related genes in doxorubicin-induced senescent human dermal fibroblasts but their secretome does not trigger a paracrine fibrotic response in non-senescent cellsSemantic proximity Read ↗

Differential Expression of Extracellular Matrix Proteins in Senescent and Young Human Fibroblasts: a Comparative Proteomics and Microarray StudySemantic proximity Read ↗

Differential expression of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged human fibroblastsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.