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Cell Senescence-Independent Ageing of Human Skin

2022-08-15

Abstract excerpt

Skin ageing is defined in part by collagen depletion and fragmentation that leads to a loss of mechanical tension. This is currently believed to reflect, in part, the accumulation of senescent cells. We compared the expression of genes and proteins for components of the extracellular matrix (ECM) as well as their regulators and found that senescent cells produced more matrix metalloproteinases (MMPs) than prolifer...

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Literature Corpus work
72e7ca6c-e602-5084-8156-fbb93b99e859
DOI
10.1101/2022.08.15.504045
Open publication

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Cell Senescence-Independent Ageing of Human SkinDOI 10.1101/2022.08.15.504045
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